Copyright © 2021 IBM Watson Health. Clodronate (clodronate disodium, Bonefos®) is a non-nitrogen-containing bisphosphonate that inhibits osteoclast activity, and thereby inhibits bone resorption. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. 1600 mg por dia, em dose única. Generic name: clodronate. Previous Drug Generic - Next Drug Generic. Brand Name: Clophosome ® Active: clodronate disodium. You may have sodium clodronate for 1 of the following reasons: to treat high blood calcium (hypercalcaemia) classificação não disponibilizada; não usar. Each capsule contains the equivalent of … Weight: 02 kg: Quantity: 5 ml (5ml Clodronate Liposomes), 10 ml (10ml Clodronate Liposomes), 15 ml (15ml Clodronate Liposomes), 20ml (20ml Clodronate Liposomes), 25 ml (25ml Clodronate Liposomes), 30 ml (30ml Clodronate Liposomes), 40 ml (40ml Clodronate Liposomes), 50 ml (50ml Clodronate Liposomes), 60 ml (60ml Clodronate Liposomes), 70 ml (70ml Clodronate Liposomes), 80 ml (80ml Clodronate … Description and Brand Names. refrigeração (2-8°C): 24 horas. Clodronate works by reducing the breakdown of bone.This medication may be available under multiple brand names and/or in several different forms. 12 Equine Key Opinions Leaders in English Performance, Western Performance, 1. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SODIUM CLODRONATE. Manufacturers of Clodronate in Pakistan. Popular Products. O MedicinaNET é o maior portal médico em português. Você está em: EY = Eye. temperatura ambiente (15 - 25°C): 24 horas. It is also called Bonefos, Clasteon, and Loron 520 This content does not have an Arabic version. Descriptions. Reações mais comuns (sem incidência definida): Fechamento de Forame Oval Patente ou Anticoagulação em Comparação Com Antiplaquetários Após AVC, Diretriz da SBC Para Gravidez na Mulher Cardiopata (parte 5/17), Risco de Suicídio e Morte Cardiovascular Após o Diagnóstico de Câncer, 6 Medicamentos Utilizados no Manejo Das Neoplasias, Infecção Latente Por M. Tuberculosis e Atualização Terapêutica - Dr. Marcelo Litvoc - 50 Min - 09/1, Estratégia Transfusional Liberal ou Restritiva Após Cirurgia de Quadril em Pacientes de Alto Risco, Suporte Avançado - Dr. Ricardo Casalino Sanches de Moraes - 52 Min - 11/10, 3.4 Medicamentos Utilizados no Tratamento da Gota, Manual de Implementação do Checklist: Parte II - Antes de Iniciar a Cirurgia. Sodium clodronate (Bonefos, Clasteon, Loron) Sodium clodronate is a type of bisphosphonate. Patients must be adequately hydrated before treatment and renal function must be monitored. Few diseases are as dehumanizing and as damaging to a … This medicine is available only with your doctor's prescription. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). CLODRONATO ABC Active Ingredient Clodronate 100 mg/3.3 ml injectable solution - 6 ampoules 100 mg/3.3 ml injectable solution - 12 ampoules 300 mg/10 ml solution for infusion I.V. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released. Disclaimer. Reúne recursos indispensáveis e conteúdos de ponta contextualizados à realidade brasileira, sendo a melhor ferramenta de consulta para tomada de decisões rápidas e eficazes. Bonefos [DSC]; Clasteon. Background. A dose máxima diária é de 3200 mg. A duração do tratamento é, em geral, de 6 meses. • doses em termos de Clodronato dissódico. This multi-page article lists pharmaceutical drugs alphabetically by name. Read More. BV = Blood vessels (circulation) BR = Brain. inibe a reabsorção óssea que leva a aumento do cálcio no sangue. •com 1 copo cheio de água, em jejum, pelo menos 30 minutos antes do café da manhã. Sodium clodronate (as tetrahydrate). It is also used to treat the increased amount of calcium in the blood (hypercalcemia) that may occur with some kinds of cancer. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use and handling. Do not take sodium clodronate at the same time as food or other medications because they may prevent its absorption. THE GOOD NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate. By mouth. Estabilidade após diluição com Cloreto de Sódio 0,9% ou Glicose 5%. Tribo™ Human IFN gamma ELISA Kit; Tribo™ Human β2-microglobulin ELISA Kit; Human TNFꭤ ELISA kit; 1 step and 1hr; Fast Human TGF-β1 ELISA Cápsula 400 mg: Bonefós Uso injetável. Both types of Clophsome ® are offered in the standard suspension form fo rthe convenience of use, the high potency form fo rdosing of high cotent with limited small volume and the lyophilized forms for the long shelf-life. Genérico: não clodronato dissódico tetraidratado equivalente a clodronato dissódico Uso oral. All rights reserved. Clodronate, Disodium Salt, CAS: 22560-50-5, is A bisphosphonate apoptosis inducing agent. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. inflamação aguda do estômago ou intestino; diminuição da função renal. Developer and worldwide provider of clodronate liposomes: Delivery on demand + Worldwide shipping & Easy Online Ordering 24/7 - Please Contact Us Dermatológico: hipersensibilidade na pele. BM = Bone marrow. Treatment for: Breast Cancer, Adjuvant. setTimeout("$('adwordstopo').hide();", 10000); Injetável (solução) 1500 mg/25 mL: Bonefós. Advertising revenue supports our not-for-profit mission. •interromper o tratamento se ocorrer comprometimento da função dos rins. Clodronato dissódico (solução) 300 mg/5 mL – Infusão intravenosa. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Portions of this document last updated: Feb. 01, 2020. It is a capsule that you take by mouth. This site complies with the HONcode standard for trustworthy health information: verify here. Cited in 1 publications Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente. Name of the medicine. Clodronate RX_link No information avaliable Clodronate fda sheet Clodronate msds (material safety sheet) Clodronate MSDS. Diluente: Cloreto de Sódio 0,9%. •realizar periodicamente exames de sangue e da função do fígado. Clodronate has been extensively used in patients with advanced breast cancer, and is generally well tolerated. Volume: 500 mL. DA = Draining area of lymph node. Clodronate belongs to a family of medications known as bisphosphonates. Back to top. Company: Berlex, Inc. hipercalcemia devido a tumores malignos ou metástases ósseas; osteólise (dissolução do osso) devido a metástase de tumores sólidos (câncer de mama, próstata ou tireoide) ou devido a neoplasia sanguínea (mieloma múltiplo). Lipid composition: phosphatidylcholine and cholesterol. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Brands / Trade Names of Clodronate. Mayo Clinic does not endorse companies or products. CAS: 22560-50-5, 7 mg/mL . •doses em termos de Clodronato dissódico. It is used to treat high calcium levels in patients with cancer. Kanis JA(1), McCloskey EV. medicamentos C. setTimeout("$('adwords').hide();", 10000); Bulk solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0-7.5 Drug information provided by: IBM Micromedex. The bad news is that clodronate is not directly available in the United States. Share this page. Clodronate is not metabolised and most of the dose appears in the urine within a few days. Permanecemos com suporte aos nossos inscritos através do e-mail info@medicinanet.com.br. Clodronate is also used to treat cancer that has spread to bones (bone metastases) due to different types of tumours. - 6 ampoules Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients with breast cancer or multiple myeloma. Clodronato (Oral; Injetável) (substância ativa) Referência: Bonefós (Bayer). Back to top. Sodium clodronate is used with other drugs to reduce the breakdown of bone caused by cancer that has spread to the bones. Parecoxib. Severity of interaction: Moderate Evidence for interaction: Study. Take this medication 1 to 2 hours (depending on your brand) before or 1 to 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. Macrophage Depletion Kit (Mannosylated) Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): 6 horas. Diluente: Cloreto de Sódio 0,9% ou Glicose 5%. Many drugs have more than one name and, therefore, the same drug may be listed more than once. Who? Clodronate. Clodronato dissódico tetraidratado equivalente a clodronato dissódico. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Clodronic Acid (Oral Route, Injection Route), FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Inicial It is used to treat hypercalcemia (high blood calcium) for people who have cancer. MF: CH2Cl2O6P2Na2, MW: 288.86. All products: If you have an allergy to clodronate … This content does not have an English version. Parecoxib is predicted to increase the risk of renal impairment when given with clodronate. Clodronate DRUG NAME: Clodronate SYNONYM(S): Clodronate disodium, clodronic acid, Cl 2MDP, dichloromethylene bisphosphonate, disodium clodronate, sodium clodronate COMMON TRADE NAME(S): CLASTEON®, BONEFOS ; OSTAC CLASSIFICATION: Bone metabolism regulator. MedicinaNET - Todos os direitos reservados. Clodronato dissódico (solução) 1500 mg/25 mL – Infusão intravenosa. (claw-DROE-nate) is a drug that is used to treat cancer which has spread into the bones (bone metastases). What do I need to tell my doctor BEFORE I take this drug? Clodronate, Disodium Salt - CAS 22560-50-5 - Calbiochem 1 Product Result | Match Criteria: Product Name Injetável (solução) 1500 mg/25 mL: Bonefós Injetável (solução) 300 mg/5 mL: Bonefós O que é Clodronate Brand Names Mixture No information avaliable; Clodronate Chemical_Formula CH 4 Cl 2 O 6 P 2. •evitar deitar por pelo menos 30 minutos. Brand names and generic names are differentiated by the use of capital initials for the former.. See also the list of the top 100 bestselling branded drugs, ranked by sales. For SODIUM CLODRONATE. Manufacturer advises avoid. LEGENDS: AL = Alveoli in lung. dados não disponibilizados; não amamentar. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Volume: 500 mL. 1997 Oct 15;80(8 Suppl):1691-5. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. About Us. Adverse reactions include renal insufficiency and hypocalcaemia. inibidor da reabsorção óssea [pirofosfato (derivado); ácido clodrônico (sal do); bifosfonato]. Purified talc, calcium stearate, anhydrous colloidal silica, lactose, gelatin, purified water, iron oxide red, iron oxide yellow, Tekprint SW-9008 black ink and titanium dioxide. GU = Gut (intestines) It is used to stop bone loss. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Clodronate Synthesis Reference No information avaliable Hematológico: diminuição do cálcio no sangue. Perspectives from an Equine Expert Panel on Clodronate Use in Horses. Clodronate is predicted to decrease the effects of parathyroid hormone. Bonefos Bayer, United Kingdom; Bayer, Tunisia; Er-Kim, Turkey; IFET, Greece Cancer. Brand name: Bonefos. Drug information provided by: IBM Micromedex. All rights reserved. geniturinário: eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Excipients Capsules. Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. You might have it as a treatment for a number of cancers that affect the bones such as myeloma and secondary breast cancer. Site designed by Pharma Professional Services and developed by Hasan Computing Systems. Each standard macrophage depletion kit contains one vial of Clodronate encapsulated liposomes (Clodrosome) and one vial of plain liposome for control (Encapsome) with the same lipid composition as Clodrosome. For Adult. Author information: (1)World Health Organization Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, United Kingdom. Generic names: clodronate disodium, clodronic acid disodium tetrahydrate; Brand names: Clasteon, Clastoban, Climaclod, Clodeosten, Clodran, Clodron, Clody, Difosfonal, Disdual, Lodronat, Loron, Lytos, Mebonat, Moticlod, Niklod, Ossiten, Ostac, Osteonorm, Osteostab, Sindronat; References ↑ 1.6 g daily in 1–2 divided doses, then increased if necessary up to 3.2 g daily in 2 divided doses. Clodronate. Share this page on Facebook Share this page on Twitter Share this page on LinkedIn Share this page by email Share this page by URL. Clodronate. It is also used to treat a high level of calcium in the blood that may occur with some cancers. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. 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And Privacy Policy linked below hydrated before treatment and renal function must be adequately hydrated before treatment and function... ; bifosfonato ] cancer, and is generally well tolerated – Infusão intravenosa Brain. Pirofosfato ( derivado ) ; ácido clodrônico ( sal do ) ; bifosfonato ] be listed more one. That is used to treat hypercalcemia ( high blood calcium ) for people have. In Horses may occur with some cancers of cancers that affect the bones from another part of body! Bone cancer—a drug named clodronate a wide variety of health topics 1 copo cheio de água, em,... ) 300 mg/5 mL – Infusão intravenosa em função da pandemia do informamos! Of tumours ( bone metastases ) Computing Systems ; diminuição da função.! Known as bisphosphonates se ocorrer comprometimento da função renal best-sellers and special offers on books newsletters... To clodronate … Brand name: Clophosome ® Active: clodronate disodium is generally well.! 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